Lake Nona Medical City Vacation Packages

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    Save up to CA $4,200 when you book a flight and hotel together*
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The Latest Lake Nona Medical City Vacation Packages

Price found within the past 48 hours. Click for updated prices.
  • Jan 9 - Jan 14

    Westgate Town Center Resort + Flight

    Kissimmee
    5 nights
    4.0 star property
    8.4/10 - Very good (2,077 reviews)
    Roundtrip • Toronto (YYZ) - Orlando (MCO)
    YYZ - MCO • Nonstop MCO - YYZ • Nonstop
    Save 100% on your flight
    CA $993
    CA $522
    per traveller
    found 1 day ago
    Westgate Town Center Resort
  • Jan 14 - Jan 18

    Margaritaville Cottages Orlando by Vstays with H2O Waterpark + Flight

    Kissimmee
    4 nights
    4.0 star property
    9.2/10 - Wonderful (1,000 reviews)
    Roundtrip • Toronto (YTO) - Orlando (MCO)
    YYZ - MCO • Nonstop MCO - YYZ • Nonstop
    CA $1,791
    CA $996
    per traveller
    found 1 day ago
    Margaritaville Cottages Orlando by Vstays with H2O Waterpark
  • Jan 24 - Jan 28

    Westgate Cocoa Beach Resort + Flight

    Cocoa Beach
    4 nights
    4.0 star property
    8.6/10 - Excellent (578 reviews)
    "The beaches across the street. The pools are nice however I had a room right next to the pool and they play music up until 9:00pm at night. So if you just trying to rest that will not happen. The music just kept playing all day long."
    Reviewed November 8, 2026
    Roundtrip • Toronto (YYZ) - Orlando (MCO)
    YYZ - MCO • Nonstop MCO - YYZ • Nonstop
    CA $1,703
    CA $966
    per traveller
    found 1 day ago
    Westgate Cocoa Beach Resort
  • Jan 15 - Jan 21

    Meliá Orlando Celebration + Flight

    Celebration
    6 nights
    4.0 star property
    8.8/10 - Excellent (1,645 reviews)
    Roundtrip • Toronto (YTO) - Orlando (MCO)
    YYZ - MCO • Nonstop MCO - YYZ • Nonstop
    CA $1,659
    CA $974
    per traveller
    found 1 day ago
    Meliá Orlando Celebration
  • Dec 18 - Dec 23

    Evermore Orlando Resort + Flight

    Orlando
    5 nights
    4.0 star property
    9.6/10 - Exceptional (860 reviews)
    Roundtrip • Hamilton (YHM) - Orlando (MCO)
    YHM - MCO • Nonstop MCO - YHM • Nonstop
    CA $3,953
    CA $2,384
    per traveller
    found 1 day ago
    Evermore Orlando Resort

Where to stay in Lake Nona Medical City

Find the best Lake Nona Medical City areas and neighborhoods for the activities you enjoy most.

Bay Lake

Home to all four Walt Disney World Resort theme parks and one water park, this city offers endless entertainment, including Disney's Fort Wilderness Resort & Campground and Magnolia and Palm Golf Courses.

International Drive District

Adventure activities, iconic attractions, shopping and world-class dining destinations make this famous street one of Orlando’s most popular tourist attractions.

Florida Center

While visiting Florida Center, you might make a stop by sights like Universal Orlando Resort and Universal Studios Florida.

Champions Gate

Abundant dining options and pristine golf courses are well-reviewed features of Champions Gate. Make a stop by top sights like ChampionsGate Golf Club while you're exploring the area.

Reunion

The waterparks and pristine golf courses are top of the list for many visitors to Reunion. A stop by Reunion Resort Golf Course or Jack Nicklaus Course might round out your trip.

What to do near Lake Nona Medical City

Lake Nona Medical City Hotel Deals

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Frequently Asked Questions

How much does a Lake Nona Medical City vacation package cost?

The cheapest Lake Nona Medical City package is CA $522, so your dream trip can become a reality — without burning a hole in your pocket. Combine flights, hotels and car rentals to tailor make a package that suits your travel style.

How do I get a cheap travel package to Lake Nona Medical City?

Find flights that fit your busy schedule, add a hotel to your booking and watch the savings rack up with a Lake Nona Medical City vacation package. It's as easy as that! From flights and hotels to tours and rental cars, Expedia makes traveling cheap and easy. And with more than 550 air carriers and 1,000,000 hotel options globally to pick from, you won't be short of choice.

Where should I stay in Lake Nona Medical City?

With loads to explore in Lake Nona Medical City, it'd be convenient for you to stay close to its attractions. Nemours Childrens Hospital, VA Medical Center at Lake Nona and University of Central Florida College of Medicine are some fascinating ones to add to your to-do list.

What are the top hotels in Lake Nona Medical City?

Make a reservation at Residence Inn Orlando Lake Nona. It's one of the area's most sought-after properties. Another reputable option in Lake Nona Medical City is Courtyard Orlando Lake Nona.

How far in advance should I book my Lake Nona Medical City vacation?

It depends on the airline, but you can generally look up international fares on Expedia up to a year in advance. While it's generally a good idea to book ahead of time, lucky customers occasionally score a cheaper ticket just weeks prior to the date of departure.

What does an Expedia Lake Nona Medical City travel package include?

Expedia has everything you need to organize your Lake Nona Medical City getaway, but what goes into your package is totally up to you. Choose from a combination of hotels, rental cars and flights. In search of some experiences or tours to keep you busy? Once you've made your booking, you can add them too. Whatever your budget or style, there's a deal to match your needs.

What should I know before booking a Lake Nona Medical City travel package?

Locking in all the parts of your escape together is a great way to save. Combine your airfares, rental cars and hotels into one package. But hotels aren't your only option. Expedia has all types of properties, including vacation rentals like beachside villas and city apartments. The list goes on!

Can I choose my airline with a Lake Nona Medical City Expedia vacation package?

Yes — and it's simple too. Expedia has access to more than 550 partner airlines worldwide. Our vacation packages give you the freedom to take your pick of available flight, hotel or activity options that fit your needs.

If I'm not able to travel, can I cancel my Lake Nona Medical City vacation package?

Don't worry if you're rethinking your Lake Nona Medical City vacation package — you can cancel or amend your booking. And if you've booked it within 24 hours, you may be able to do it at no cost. However, bookings made more than 24 hours ago may incur a fee from your airline, hotel or car rental company. We know life can throw the occasional spanner in the works, so look up our Customer Service Portal if that occurs. When you're ready to make changes, we'll be here to help.

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.